女,藥理(lǐ)學(xué)博士,主任藥師,博士生導師。中(zhōng)國(guó)藥學(xué)會醫(yī)院藥學(xué)專業委員會婦産(chǎn)科(kē)藥學(xué)專業組副組長(cháng),中(zhōng)國(guó)婦幼保健協會藥事管理(lǐ)專業委員會副主任委員,中(zhōng)國(guó)藥學(xué)會科(kē)技(jì )開發中(zhōng)心“智愛媽媽”安(ān)全用(yòng)藥科(kē)普促進行動專家指導委員會副主任委員,浙江省醫(yī)師協會臨床藥師專家委員會第一屆副主任委員,浙江省藥學(xué)會醫(yī)院藥學(xué)專業委員會委員婦兒學(xué)組組長(cháng),浙江省藥學(xué)會醫(yī)院藥學(xué)專業委員會委員和浙江省藥學(xué)會藥劑專業委員會委員,浙江省醫(yī)院藥事管理(lǐ)質(zhì)控中(zhōng)心專家委員會委員,中(zhōng)國(guó)老年保健醫(yī)學(xué)研究會老年合理(lǐ)用(yòng)藥分(fēn)會(第一屆)委員,浙江省毒理(lǐ)學(xué)會第一屆臨床藥物(wù)治療安(ān)全專業委員會委員,浙江省藥理(lǐ)學(xué)會藥源性疾病學(xué)委員會委員,浙江省藥理(lǐ)學(xué)會藥物(wù)治療監測研究專業委員會委員,《中(zhōng)國(guó)現代應用(yòng)藥學(xué)》雜志(zhì)常務(wù)編委。浙江省醫(yī)學(xué)會醫(yī)學(xué)鑒定專家庫成員。主要從事蛋白、多(duō)肽藥物(wù)的緩控釋制劑研究以及基因靶向研究。主持國(guó)家自然科(kē)學(xué)基金2項,省自然科(kē)學(xué)基金2項。參編《藥物(wù)新(xīn)劑型》、《婦産(chǎn)科(kē)臨床藥物(wù)治療學(xué)》、《藥品超說明書使用(yòng)循證評價》等書籍5本;獲國(guó)家發明專利授權4項。發表SCI收錄論文(wén)21篇。獲浙江省科(kē)學(xué)技(jì )術獎三等獎1項。
發表的SCI收錄論文(wén):
1 C.H. Zheng, W.Q. Liang, H.Y. Yu and H.L. Chen. Evaluation of different analytical methods of proteins in PLGA Microspheres. Pharmazie 2004; 59 (3): 232-233.
2 C.H. Zheng, J.Q. Gao, W.Q. Liang, H.Y. Yu and Y.L. Zhang. Optimization and characterization of chitosan-coated alginate microcapsules containing albumin. Pharmazie. 2005; 60 (6): 434-438.
3 Zheng Cai-Hong, Liang Wen-Quan and Zhang Ye-Ping A protein delivery system: biodegradable alginate-chitosan-poly (lactic-co-glycolic acid) composite microspheres. Biochemical and Biophysical Research Copmmunications 2004; 323: 1321-1327.
4 Cai-Hong Zheng, Jian-Qing Gao, Wen-Quan Liang,He-Yong Yu and Yi-li Zhang. Effects of additives and processing parameters on the initial burst release of protein from poly (lactic-co-glycolic acid) microspheres. PDA Journal of Pharmaceutical Science and Technology, 2006; 60 (1): 54-59.
5 Y. Wang, J.Q. Gao, H.L. Chen, C.H. Zheng and W.Q. Liang. Pluronic F127 gel effectively controls the burst release of drug from PLGA microspheres. Pharmazie 2006; 61 (4): 367-368.
6 Ye Wang, Jian-Qing Gao, Cai-Hong Zheng, Dong-Hang Xu and Wen-Quan Liang. Biodegradable and complexed microspheres used for sustained delivery and activity protection of SOD. Journal of Biomedical Materials Research Part B, 2006 79B:74-78
7 Cai-Hong Zheng, He-Yong Yu, Jian-Qing Gao, Xiao-Yi Sun, Wen-Quan Liang. Hydrophilic biodegradable microspheres of interferon-alpha and its pharmacokinetics in mice. Journal of Biomedical Materials Research Part B, 2008, 85 (1):225-230 (IF: 2.030)
8. Chen G, He CX, Xu DH, Liu L, Zhang FJ, Xu JY, Zheng CH, Gao JQ, Yan M. Composite microspheres induced the sustained release and the control of the initial release of water soluble drug. Pharmazie 2009, 64(4):284-6
9. Cai-Hong Zheng, Wen-Quan Liang. A one-step modified method to reduce the burst initial release from PLGA microspheres. Drug Delivery, 2010, 17 (2):77-82 (IF: 1.246)
10. Xiaoling Zheng, Yongzhuo Huang, Caihong Zheng*, Siyu Dong, Wenquan Liang. Alginate-chitosan-PLGA composite microspheres enabling single-shot hepatitis B vaccination. AAPS J 2010, 12 (4):519-524. (IF: 3.942)
11. S Dong, S Wang, C Zheng, W Liang, and Y Huang. An in situ-forming, solid lipid/PLGA hybrid implant for long-acting antipsychotics. Soft Matter 2011, 7:5873-5878
12. Meng-Dan Zhao, Yan-Mei Sun, Guo-Fang Fu, Yong-Zhong Du, Feng-Ying Chen, Hong Yuan, Cai-Hong Zheng, Xin-Mei Zhang, Fu-Qiang Hu. Gene therapy of endometriosis introduced by polymeric micelles with glycolipid-like structure. Biomaterials 2012, 33:634-643.
13. Shuqing Zhou, Xiaoling Zheng, Caihong Zheng*, Fan Qu, Xuefen Cai, Juanhua Xu. A thermosensitive gel formulation of an empirical traditional chinese precription for treating cervical erosion. Acta Pharmaceutica Sinica B. 2012; 2(5):495-501.
14. Ye Wang,ab Ergang Liu,b Xiaoyi Sun,c Pengyu Huang,a Hao Long,a Hua Wang,d Xin Yu,a Caihong Zhenge and Yongzhuo Huang*. Pluronic L61 as a long-circulating modifier for enhanced liposomal delivery of cancer drugs. Polym. Chem., 2013,4, 2958-2962 (IF: 5.321)
主持的科(kē)研項目:
1. 鄭彩虹,周淑青,張葉萍,汪鳳梅,虞和永,蔣惠娣,梁文(wén)權. 木(mù)犀草(cǎo)素複合骨架緩釋片的研制. 2005C054, 2萬元, 浙江省中(zhōng)醫(yī)藥科(kē)技(jì )計劃項目. 2005/1-2007/6
2 . 鄭彩虹,王靈傑,周淑青,虞和永,張葉萍,許東航,梁文(wén)權. 乙肝疫苗PLGA複合微球的制備及免疫學(xué)效應評估. 2005TG022, 2萬元, 浙江省醫(yī)藥衛生科(kē)技(jì )成果推廣項目2005/7-2007/6
3. 鄭彩虹,錢曉丹,阚連娣,虞和永. 聚離子親水凝膠對SOD-PLGA微球的修飾. 20050983, 1萬元, 浙江省教育廳一般項目2005/7-2008/12
4.鄭彩虹, 潘碧雲, 樓亞敏, 高惠娟, 周淑青, 虞和永. 曲普瑞林及其緩控釋制劑在體(tǐ)外受精(jīng)-胚胎移植中(zhōng)的用(yòng)藥. 1萬元,浙江省藥學(xué)會醫(yī)院藥學(xué)科(kē)研項目2008ZYY08 2008/10-2010/10
5.鄭彩虹, 周淑青, 吳巧愛, 蔡雪(xuě)芬, 鄒韻, 莊亞玲, 虞和永, 蔣惠娣. 選擇性負載不同藥物(wù)的一種溫敏凝膠的研制. 2008ZA010,10萬元,浙江省中(zhōng)醫(yī)藥科(kē)技(jì )計劃重點項目 2008/01-2010/12
6. 鄭彩虹, 葉轶青, 岑航輝, 汪鳳梅, 莊亞玲, 鄭曉玲. 實現生長(cháng)因子有(yǒu)序釋放的複合載體(tǐ)在軟骨誘導分(fēn)化中(zhōng)的作(zuò)用(yòng). Y2080185,6萬元,浙江省自然科(kē)學(xué)基金項目 2009/01-2011/12
7. 鄭彩虹,趙夢丹,陳麗莉,葉轶青,梁文(wén)權,周淑青,鄭曉玲. 靶向腫瘤樹突狀細胞的還原觸發型SiRNA共轭物(wù)膠束的設計及其分(fēn)化調控. 81173000,62萬元,國(guó)家自然科(kē)學(xué)基金面上項目 2012/01-2015/12
主參的科(kē)研項目:
1. 基因給藥的分(fēn)子生物(wù)藥劑學(xué)研究. 30371692,20萬元,國(guó)家自然科(kē)學(xué)基金,2004.01-2006.12
2. 實現體(tǐ)内細胞定向遊走的新(xīn)型免疫因子載體(tǐ)的構建. 30572270,20萬元,國(guó)家自然科(kē)學(xué)基金,2006.01-2008.12
3. 高穩定易吸收多(duō)肽蛋白的設計和應用(yòng). 2006C21091,浙江省科(kē)技(jì )攻關項目,2006.01-2008.12
國(guó)家發明專利
1. 梁文(wén)權, 鄭彩虹. 三重複合微球制劑及其制備方法. 專利号為(wèi):200410016067.0;證書号為(wèi):277195.
2. 鄭彩虹, 梁文(wén)權. 乳酸-羟乙酸共聚物(wù)複合微球制劑的制備方法. 專利号為(wèi):200610155050.2;證書号為(wèi):620981.
3. 鄭彩虹, 鄭曉玲, 周淑青. 一種治療宮頸糜爛的凝膠制劑及其制備方法. 國(guó)家發明專利專利号:ZL201110255408.X ; 證書号:1118615. (2013年1月授權)
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